2014 – present: Quantitative Developmental Biology
- Nodal is a short-range morphogen with activity that spreads through a relay mechanism in human gastruloids
L Liu, A Nemashkalo, L Rezende, JY Jung, S Chhabra, MC Guerra, I Heemskerk, A WarmflashNature Communications (2022)
- Roadmap for the multiscale coupling of biochemical and mechanical signals during development
PF Lenne, E Munro, I Heemskerk, A Warmflash, L Bocanegra-Moreno, …Physical biology (2021)
- Efficient differentiation of human primordial germ cells through geometric control reveals a key role for Nodal signaling
K Jo, S Teague, B Chen, HA Khan, E Freeburne, H Li, B Li, J Spence, I HeemskerkbioRxiv (2021)
- Full of potential: Pluripotent stem cells for the systems biology of embryonic patterning
I Heemskerk
Developmental Biology (2019) - A novel self-organizing embryonic stem cell system reveals signaling logic underlying the patterning of human ectoderm
G Britton, I Heemskerk, R Hodge, AA Qutub, A WarmflashDevelopment (2019); bioRxiv (2019)
- Opening the black box: Stem cell–based modeling of human post-implantation development
K Taniguchi, I Heemskerk, DL GumucioJournal of Cell Biology (2019)
- Rapid changes in morphogen concentration control self-organized patterning in human embryonic stem cells
I Heemskerk, K Burt, M Miller, S Chhabra, MC Guerra, L Liu, A WarmflasheLife 8 (2019); bioRxiv (2017)
- Morphogen and community effects determine cell fates in response to BMP4 signaling in human embryonic stem cells
A Nemashkalo, A Ruzo, I Heemskerk, A WarmflashDevelopment (2017); bioRxiv (2017)
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O Loza*, I Heemskerk*, N Gordon-Bar, L Amir-Zilberstein, D Sprinzak
eLife (2017) - Differential growth triggers mechanical feedback that elevates Hippo signaling
Y Pan, I Heemskerk, C Ibar, BI Shraiman, KD Irvine
Proceedings of the National Academy of Sciences (2016) - Pluripotent stem cells as a model for embryonic patterning: From signaling dynamics to spatial organization in a dish
I Heemskerk, A Warmflash
Developmental Dynamics (2016) - Tissue cartography: compressing bio-image data by dimensional reduction
I Heemskerk*, SJ Streichan*
Nature methods - Active Tension Network model of epithelial mechanics
N Noll, M Mani, I Heemskerk, S Streichan, BI Shraiman
Nature Physics (2017), arXiv:1508.00623 (2015) - Dynamic clonal analysis based on chronic in vivo imaging allows multiscale quantification of growth in the Drosophila wing disc
I Heemskerk, T Lecuit, L LeGoff
Development (2014)
2009 – 2012: String Theory
- Perspectives on Bulk Locality in Gauge/Gravity Duality
I Heemskerk (2012)
Thesis (is mostly just the papers below, but for the big picture read the introduction) - Bulk and transhorizon measurements in AdS/CFT
I Heemskerk, D Marolf, J Polchinski, J Sully
Journal of High Energy Physics 2012 (10), 1-29 - Construction of bulk fields with gauge redundancy
I Heemskerk
Journal of High Energy Physics 2012 (9), 1-13 - Holographic and Wilsonian renormalization groups
I Heemskerk, J Polchinski
Journal of High Energy Physics 2011 (6), 1-28 - More holography from conformal field theory
I Heemskerk, J Sully
Journal of High Energy Physics 2010 (9), 1-19 - Holography from conformal field theory
I Heemskerk, J Penedones, J Polchinski, J Sully
Journal of High Energy Physics 2009 (10), 079